African Journal of Respiratory Medicine received 855 citations as per google scholar report
Lymphomatoid granulomatosis is a rare Epstein Barr virus-driven B cell lymphoproliferative disease. It is a distinctive type of malignant lymphoma associated commonly with immunosuppression. The lungs are the most commonly involved organs. We present a case report of a 45-year-old immunocompetent gentleman who was diagnosed with pulmonary lymphomatoid granulomatosis. He presented with symptoms of an upper respiratory tract infection and persistent fever. His Biofire Adenovirus PCR test on the throat swab was positive with a normal Chest X-ray and CRP 47 and PCT 0.17. His clinical condition deteriorated despite treatment with Tamiflu for four days and he developed respiratory distress, hypoxaemia and septic shock. Bronchoscopy and lavage results showed Adenovirus infection only, normal cytology and negative for fungi and bacteria. A lung biopsy confirmed the diagnosis of lymphomatoid granulomatosis, he was treated for EBV with Gancyclovir with good clinical response and referred to an Oncologist.
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